A third lineage of mimivirus (A) was resistant to the virophage. Supposing the resistance might have roots in a CRISPR-like mechanism, Raoult’s team sequenced genomes from the three giant-virus ...
Using a new CRISPR-based methodology for modulating DNA structure to enact epigenetic control over specific genes, a team of researchers has identified a “master regulator” gene capable of improving T ...
Schmid Burgk and first author of the paper. "For a conventional CRISPR screen, it often takes months to precisely separate the cells according to their function." Another advantage of the new ...
AZoLifeSciences on MSN3 个月
A New Understanding of Viral Infection
The CRISPR screen also identified CD163 ... “If we can prevent the virus from entering a cell by disrupting this initial ...
Then Crispr came along—the elegant enzymatic apparatus ... As for delivery systems, the family of adeno-associated virus (AAV) vectors already provides the ability to achieve in vivo editing ...