Prior irradiation or chemotherapy. Bone marrow suppression. Azotemia. Monitor platelets, hemoglobin, WBC and differential at start of therapy and prior to each course; discontinue if WBC <3 ...

Medications such as chemotherapy drugs cause drug-induced bone marrow suppression. Chemotherapy kills off all rapidly dividing cells such as cancer cells, but also damages or kills stem cells that ...

Described in a new paper in Cell Stem Cell, the bone marrow model and the demonstration of its large-scale production and automation could advance fields as diverse as drug development by enabling ...