Researchers have identified a second dopamine-driven "clock" in the brain that works alongside the biological 24-hour cycle, ...

His focus on the PVT stems from evidence found more than 20 years ago that mitochondria in the brain were dysfunctional in people who had experienced bipolar disorder 1. His early studies with ...

Discover how the body’s sleep-wake clocks and dopamine-driven rhythm, influence bipolar mood swings, offering novel treatment ...

In the largest genome-wide study of bipolar disorder to date, an international team involving UCL researchers has identified 298 regions of the genome ...

The genetic architecture underlying bipolar disorder varied with subtype and how cases were identified. A brain structure called the amygdala, and its connections with another region, the prefront ...

A brain rhythm working in tandem with the body's natural sleep-wake cycle may explain why bipolar patients alternate between mania and depression, according to new research. The McGill University ...

The project supports efforts by the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium's Bipolar Disorder Working Group (ENIGMA-BD), which Ching chairs. ENIGMA-BD has fostered ...