Microtubules are cylindrical polymers composed of alpha and beta tubulin. They are a major component of the cytoskeleton and mediate crucial cellular functions including formation of the mitotic ...
You have full access to this article via your institution. There are several methods for removing MAPs from MTP to produce purified tubulin: using DEAE-Sephadex or phosphocellulose chromatography ...
Proteins containing disordered domains perform many important cellular functions. My lab currently has two main projects, one to dissect the role of tubulin's C-terminal tail in microtubule structure ...