To do a pharmacogenomic screen ... an array of cells, each containing a deletion of an individual gene. In the 2014 paper that first described such screens, the researchers took a CRISPR-edited ...

Using a new CRISPR-based methodology for modulating DNA structure to enact epigenetic control over specific genes, a team of researchers has identified a “master regulator” gene capable of improving T ...

Schmid Burgk and first author of the paper. "For a conventional CRISPR screen, it often takes months to precisely separate the cells according to their function." Another advantage of the new ...