Spironolactone is a diuretic (water pill) commonly used to treat heart failure and high blood pressure, but it can also be ...

Aldactone (spironolactone) is the most commonly used anti-androgen in the United States. It is a type of steroid that not only works as a testosterone blocker but is also used as a diuretic ...

The landmark Randomized Aldactone Evaluation Study (RALES), published in 1999, showed that spironolactone, a potassium-sparing diuretic, improves outcomes in patients with severe heart failure.

Spironolactone oral tablet is a generic drug prescribed for heart failure, high blood pressure, and other conditions in adults. It is available as the brand-name drug Aldactone. An interaction ...

However, spironolactone is associated with serious adverse events, including hyperkalemia and gynecomastia. [10,11] Consequently, clinical benefits related to the use of spironolactone are ...

Spironolactone's safety profile had been primarily generated from trials of older people with heart failure, so its safety in ...