Our findings identified three clinically meaningful factors corresponding to 'elated mania',' irritable mania' and 'psychotic mania'. These findings support the multidimensional nature of manic ...

Purpose: The efficacy and tolerability of quetiapine in the treatment of acute mania were reviewed. Summary: Five randomized, placebo-controlled trials involving quetiapine as monotherapy or ...

The Cleveland Clinic explains that mania is part of bipolar disorder. It says: "Acute mania is the manic phase of bipolar I disorder. It is defined as an extremely unstable euphoric or irritable ...

The protein kinase C (PKC) signaling cascade has been identified as a direct biochemical target for the treatment of mania. Preclinical studies and early clinical trials have shown that the ...